Highlighting key speeches from the 2010 Early Brain & Biological Development Symposium, this summary report documents major speaking points and emphasizes the cross-disciplinary importance of sensitive phases in early childhood development. This knowledge-mobilization event touches on key early and influential factors of brain experience, the impacts of stress, genetic expression, the ramifications of both abusive and positive care giving contexts, reward circuitry, and the subsequent addiction-based response systems that can develop from that brain construction.