Dr. Thomas McLellan (Treatment Research Institute) makes a compelling case for implementing science-based drug policies in North American communities. Dr. McLellan proposes reworking public policy to provide care for the estimated 60 million Americans who are not addicts, yet engage in “medically harmful use” of illegal drugs and alcohol. He proposes three pillars of a new brain-science-based drug policy: build national system of “prevention prepared communities;” screen and intervene with emerging substance abuse issues; and integrate evidence-based addictions treatments into mainstream healthcare using the chronic care model.